Monkey Shines

Monkey Shines is a 1988 American psychological horror film written and directed by George A. Romero and starring Jason Beghe, Kate McNeil, John Pankow, and Joyce Van Patten. Its plot follows a young athlete who becomes a paralyzed quadriplegic, and develops a bond with an intelligent service monkey named "Ella" who becomes homicidal after she is injected with an experimental serum of human brain tissue. It is based on the 1983 British novel of the same title by Michael Stewart.