Arrowsmith is a 1931 American pre-Code drama film directed by John Ford and starring Ronald Colman, Helen Hayes, Richard Bennett, and Myrna Loy. It was adapted from Sinclair Lewis's 1925 novel Arrowsmith by Sidney Howard, departing substantially from the book regarding Arrowsmith's womanizing and other key plot elements. The pre-Code film received four Oscar nominations, including the Academy Award for Best Picture, Best Writing, Adaptation (Howard), Best Cinematography, and Best Art Direction.